USB Overdrive 10.4

The USB Overdrive is a device driver for Mac OS X that handles any USB mouse / trackball / joystick / gamepad / media keyboard and any Bluetooth mouse from any manufacturer and lets you configure them either globally or on a per-application, per-device basis.

It works in Mac OS X 10.4 (Tiger), 10.5 (Leopard) and 10.6 (Snow Leopard) in both 32-bit and 64-bit modes.
It reads all kinds of wheels, buttons, switches and controls and assigns them to useful actions like clicking, typing, scrolling, launching, opening documents and so forth. The USB Overdrive can easily handle several USB devices at once and can assign different settings to each one.