With iGrabIt, you can create MOV files of anything on your screen.
Capture video ( with or without system audio ) and pictures from your display and save to a file, or email it with a click of a button.
Create presentations or demonstrations by configuring iGrabIt to follow the mouse cursor and capture mouse clicks.
iGrabIt captures audio from the system default audio device ( configured by running /Application/Audio MIDI Setup.app ). Thus, if you want to caputure audio from another application, you can either physically connect the audio out into the line in, or you can use soundflower which does the same thing in software.