OneWorld Dictionary by Ascendo is a leading multilingual reference tool for Apple desktops.
The free version is a good starting point for beginners.
Each language pair is comprised of over 250,000 translations. Translations include multiple meanings, part of speech, noun gender and verb tenses. One World Dictionaries integrate with Lion applications such as Safari so you can lookup words using control-click.
Being a free tool this dictionary is very handy. It is easy to learn some new expressions with the help of its phrasebook.