Tweak the settings of various GamePads to optimize the playing process on your Mac. Get joysticks and gamepads whose drivers haven't been updated to work on your Mac and use up to 5 HID devices. Set your controllers to function as a mouse cursor and buttons and save your layouts.
GamePad Companion allows you to use HID compatible devices (gamepads, joysticks, etc..) with Mac OS X. This means that you can use many of the joysticks and gamepads that haven't had their drivers updated for Mac OS X! It should be possible to simultaneously use up to 5 HID devices with GamePad Companion.