Mac users interested in Smutefy for mac generally download:
Smutefy is a small menu bar application that automatically detects and mute Spotify ads.
Start Smutefy by double clicking it in your Applications folder. Smutefy will put an icon in the right side of your menu bar. When some ad is detected by the application, the icon will change his color and will mute the system sound until the ad finishes.