QFeeder

QFeeder is an OSX 10.6 optimized Twitter client. It has a novel design based on prioritization of messages within your streams based on what you do and who you interact with.

QFeeder adds a strip of icons to the left side of your desktop that will update through the day showing your most important messages.
QFeeder watches what you do and with your input will change the order of messages so you don't miss the most important ones.