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PrimerSelect's comprehensive set of tools enables you to design and analyze primers for PCR, sequencing, probe hybridization and transcription. Enter your own primers or let PrimerSelect generate a sorted list of suggested primers for all or part of your DNA, RNA or back-translated protein template. You can accept PrimerSelect's top choice, evaluated on the thermodynamic properties for annealing reactions, or view all of the options and choose alternatives based on your specialized knowledge. PrimerSelect includes the WorkBench where you preview the effects your choices will have on reading frames and restriction sites. PrimerSelect further assists you by highlighting potential pitfalls in both standard and multiplex PCR experiments via illustrations, graphs and statistical reports. These tools enable you to limit investment in time-consuming and costly experiments to those that have the highest probability of success. PrimerSelect even lets you perform BLAST or Entrez text searches and load sequences directly from NCBI's databases.