AnimeEffects

AnimeEffects is a 2D key frame animation tool based on deformation of polygon meshes. The app provides various animation keys, such as Moving, Rotating, Scaling, Bone Deformation, Free-Form Deformation, Opacity, and Image Changing.

You can import image files such as JPEG, PNG, GIF, and PSD for animation resources. For PSD, AnimeEffects supports layer clipping and many blending modes.